
The Ultimate Guide to
NIST SP 800-161: Cyber Supply Chain Risk Management
What is NIST SP 800-161?
NIST SP 800-161, Cybersecurity Supply Chain Risk Management Practices for Systems and Organizations, guides organizations on identifying, assessing, and mitigating cybersecurity risks throughout the supply chain at all levels of their organizations. The publication integrates cybersecurity supply chain risk management (C-SCRM) into risk management activities by applying a multi-level approach that includes guidance on developing C-SCRM strategy implementation plans, C-SCRM policies, and risk assessments for products and services.
The current version of NIST SP 800-161 is Rev. 1, published in May 2022.
What are the benefits of NIST SP 800-161?
Organizations rely heavily on third-party vendors and suppliers to run their businesses, operate efficiently, and serve customers. Security issues in your supply chain can instantly become security risks for your organization. Supply chain risks often become magnified today because many organizations don’t have the processes and procedures to comprehensively manage supply chain risk.
NIST SP 800-161 can help organizations manage supply chain risk by delivering the following benefits:
- Enhanced supply chain security: By providing comprehensive guidelines for managing supply chain risks, organizations can better protect their systems from vulnerabilities and threats originating from their supply chain.
- Improved risk management: NIST SP 800-161 helps organizations identify, assess, and mitigate supply chain risks, leading to more robust risk management practices.
- Alignment with federal requirements: While not all organizations are required to comply with NIST SP 800-161, it helps federal agencies and their contractors align with federal supply chain risk management standards and expectations.
- Increased trust and resilience: Implementing supply chain risk management practices enhances the overall trust and resilience of an organization’s information systems and operations.
- Competitive advantage: Demonstrating compliance with NIST SP 800-161 can provide a competitive edge in securing federal contracts and partnerships by showcasing a commitment to supply chain security.
What types of organizations does NIST SP 800-161 apply to?
Any organization sharing sensitive customer or patient information with third parties can benefit from following NIST SP 800-161 guidelines. For example:
- Retail or e-commerce businesses storing sensitive customer information with card processors or cloud service providers
- Healthcare organizations using email providers, coding services, or cloud storage vendors to assist in the storing or transmitting of sensitive patient records
- Banking and financial service companies buying software products for marketing, accounting, or security services
How is NIST SP 800-161 organized?
The introduction section of NIST SP 800-161 outlines the document’s purpose and target audience profiles. This section also discusses the methodology for building C-SCRM guidance using NIST SP 800-39, NIST SP 800-37, Rev 2, and NIST SP 800-53, Rev 5.
Section 2 builds a business case for C-SCRM and dives into the governance, organizational structures, roles, responsibilities, and activities performed across all three C-SCRM levels: enterprise, mission and business process, and operational. Section 2 also explains the integration of C-SCRM with the enterprise-wide risk management processes described in NIST SP 800-39, including the continuous and iterative steps of framing, assessing, responding to, and mitigating risk.
Section 3 of NIST SP 800-161 provides an in-depth look at the critical success factors required for any C-SCRM program. This section discusses the integration of C-SCRM into acquisition, supply chain info sharing, awareness and training, key practices, implementing measurement controls, and dedicating resources to your C-SCRM program.
Appendix A covers C-SCRM security controls:
Supplier’s system access must be managed to prevent unauthorized release, modification, or destruction of information. Access should be limited only to the necessary type, duration, and level for authorized enterprises and monitored for impact on the supply chain.
This family expands the Awareness and Training control of FIPS 200 to include C-SCRM. It discusses the training component behind understanding supply chain security challenges and the appropriate processes and controls to mitigate cybersecurity risk in the supply chain.
Information system audit records must be created and stored to monitor, investigate, and analyze unlawful or inappropriate system activity. This control also monitors and traces all system users’ actions.
Information system controls must be assessed periodically to ensure correct function, and plans to correct any deficiencies and eliminate potential vulnerabilities must be developed and implemented. Information systems must also be continually monitored to ensure the effectiveness of controls.
Baseline configurations and inventories of information systems (e.g., hardware, software, firmware, documentation) must be established throughout the system development life cycle (SDLC). Additionally, security configuration settings must be created for all information system products.
Guidelines must be created to establish and implement plans covering emergency response, backup operations, and post-disaster recovery for information systems and supply chains.
System components must be identified and authorized in addition to individuals and processes acting on behalf of individuals within the supply chain network.
Effective incident handling capability must be established within information systems and supply chains, including adequate preparation, detection, analysis, containment, recovery, and user response activities. All incidents must be tracked, documented, and reported to appropriate officials and authorities.
Maintenance must be performed on information systems while providing adequate controls for the tools, techniques, mechanisms, and personnel involved. C-SCRM should be applied to maintenance, including assessing cybersecurity risk in the supply chain, selecting C-SCRM controls, implementing these controls, and continued monitoring to ensure proper function.
Paper and digital media must be protected across the supply chain with access limited to authorized users. Additionally, all system media must be sanitized or destroyed before disposal.
Physical access to information systems, equipment, and operating environments must be limited to authorized personnel, while physical assets, infrastructure, and information systems within the supply chain must be safeguarded from environmental hazards.
Security plans must be developed, documented, implemented, and updated for supply chain information systems that describe current security controls and set the behavior guidelines for individuals accessing the systems.
Minimum security control requirements aren’t specified by FIPS 200 for program management. However, any program management controls should be applied in a C-SCRM context, providing guidance and feedback for enterprise-wide C-SCRM activities. These controls should apply across the entire enterprise while supporting an overarching information security program.
Ensures individuals in positions of responsibility meet established security criteria for those positions and protects supply chain information systems during personnel moves like terminations and transfers. Imposes formal sanctions for those failing to comply with personnel security policies.
This is a new control family, explicitly developed to address the processing and transparency concerns of personally identifiable information (PII) within supply chains. Enterprises must build their PII processing and transparency policies and procedures with an eye on supply chain risk management and system security.
Risk to organizational operations, assets, and individuals resulting from the operating of information systems must be periodically assessed in light of maintaining effective supply chain risk management.
Sufficient resources must be allocated to adequately secure organizational information systems and ensure all third-party suppliers follow similar protocols to protect the information, applications, products, and services outsourced from the company.
Organizational communications must be monitored, controlled, and protected at both internal and external information system boundaries, employing architectural designs, software development techniques, and systems engineering principles to deliver adequate information security.
Teams must monitor information security alerts and take appropriate action to identify, report, and correct system flaws quickly. This includes protecting against malicious code at appropriate locations within information systems.
FIPS 200 doesn’t specify minimum security requirements for supply chain risk management. NIST SP 800-53 Rev. 5 established this as a new control family with SP (800-161 R1), including all SR control enhancements from SP 800-53 Rev. 5 regarding supply chain risk management.
Appendix B lists the C-SCRM controls in NIST SP 800-161 and maps them to their corresponding NIST SP 800-53 controls as appropriate.
Appendix C provides an example of a Risk Exposure Framework for C-SCRM that can help enterprises address potential and identified threats. The framework contains six examples that demonstrate how to identify vulnerabilities, describe specific threat sources, show the expected impact on the enterprise, and propose C-SCRM controls to help mitigate risk.
Appendix D provides examples of templates outlining the typical components of a C-SCRM strategy and implementation plan.
Appendix E augments the current content in NIST SP 800-161 and provides additional guidance specific to federal executive agencies on supply chain risk assessment factors, assessment documentation, risk severity levels, and risk response.
Appendix F provides a link to a web portal for departments and agencies looking to facilitate compliance with Executive Order (EO) 14028, Improving the Nation’s Cybersecurity.
Appendix G provides a detailed description of C-SCRM activities within the frame, assess, respond, and monitor steps of the risk management process.
Appendices H through K provide a glossary, list of abbreviations, resources, and revision history.
What is NIST SP 800-161 compliance?
NIST SP 800-161 compliance means that an organization has implemented and follows the guidelines and best practices outlined in NIST SP 800-161 for supply chain risk management. This involves:
- Identifying and assessing supply chain risks: The organization must identify potential risks throughout the supply chain that could impact the security, integrity, or availability of its information systems.
- Implementing appropriate security controls to mitigate these risks: The organization must apply relevant security controls, often derived from NIST SP 800-53, and adapt them to address supply chain-specific risks, including controls related to procurement, development, and deployment processes.
- Continuously monitoring and managing supply chain risks: The organization must establish ongoing monitoring and management practices to track and respond to changes in the supply chain that could introduce new risks.
- Ensuring that supply chain partners also adhere to security requirements: The organization must ensure that its supply chain partners adhere to relevant security controls and practices, extending risk management beyond the organization’s immediate boundaries.
Compliance with NIST SP 800-161 demonstrates an organization’s commitment to securing its supply chain and protecting against threats and vulnerabilities that could impact its information systems.
Is NIST SP 800-161 compliance required?
NIST SP 800-161 compliance is not mandated across all industries, but is required for federal agencies and their contractors who need to manage supply chain risks. For federal agencies, adherence to NIST SP 800-161 is a key part of their supply chain risk management strategy. For organizations working with federal agencies, adhering to NIST SP 800-161 can be crucial for maintaining contracts and ensuring that supply chain risks are effectively managed.
What are the critical success factors for a supply chain risk management program?
Section 3 of NIST SP 800-161 documents the following six critical success factors to ensure program success:
NIST 800-161: Frequently Asked Questions
How Hyperproof Supports Cybersecurity Supply Chain Risk Management
Hyperproof’s compliance operations software helps organizations implement a robust cyber supply chain risk management program. Sign up for a personalized demo to see how you can use Hyperproof to manage a C-SCRM program efficiently.

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